Massive pleural effusion and marked increase of CA-125.
نویسندگان
چکیده
The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.
منابع مشابه
بررسی ارزش تشخیصی میزان CA 125, CA 19-9, CA 15-3 مایع پلور در افتراق افیوژن پلورال بدخیم از خوش‌خیم
Background and purpose : Malignant and infectious diseases are the most frequent causes of pleural effusion. Malignant diseases produce pleural effusion through different mechanisms: lymphatic and capillary obstruction, pneumonia or atelectasia. Therefore absence of tumor cells in aspirated effusion, highly declines the sensivity of the cytologic study. For this reason, the use of tumor marke...
متن کاملSarcoidosis Presenting with Massive Pleural Effusion and Elevated Serum and Pleural Fluid Carbohydrate Antigen-125 Levels
A 55-year-old woman was admitted for an elevated serum carbohydrate antigen-125 (CA-125) level, and a left pleural effusion, which were detected at a routine health examination. Computed tomography of the chest was performed upon admission, revealing extensive bilateral paratracheal and mediastinal lymph node enlargement with a massive left-sided pleural effusion. Subsequent analysis of the ple...
متن کاملمقایسه ارزش تشخیصی تومور مارکرهای مایع پلور با سیتولوژی مایع پلور و بیوپسی پلور در اثبات وجود بدخیمی
Introduction: Cancers are the most prevalent causes of exudative pleural effusions after para-pneumonic pleural effusions. Despite the combination of the pleural fluid cytological studies and pleural biopsy, diagnosis could not be reached in an important number of cases. In an attempt to improve the value of pleural fluid analysis in the diagnosis of malignant pleural effusion, some studies...
متن کاملCA-125 concentrations in malignant and nonmalignant disease.
CA-125 is a high-molecular-mass glycoprotein expressed on the cell surface of some derivatives of embryonic coelomic epithelium. This tumor-associated antigen widely used to monitor ovarian carcinomas has been suggested as a promising noninvasive test that could differentiate benign from malignant conditions. Based on results of various studies, CA-125 measurement appears to be very useful in m...
متن کاملRole of cancer antigen-125 from pleural & ascitic fluid samples in non malignant conditions.
BACKGROUND & OBJECTIVE CA-125, an ovarian tumor marker is known to increase in non malignant conditions such as tubercular and non tubercular pleuritis and ascites. We undertook this study to evaluate non-specific rise in CA-125 levels in conditions associated with pleural effusion and ascites and also to understand the mechanism of its secretion. METHODS CA-125 levels in 38 pleural and 46 as...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 80 943 شماره
صفحات -
تاریخ انتشار 2004